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db: MATss, MATpf, MATbz families and five tier-3 candidate records (S. schoenii, P. fabianii, B. californica) - #220

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Oct 30, 2026
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Stacked on #216 (base pichia-family; retarget to main after it merges).

Candidate reference records for the SLA2-type genera whose MTL/MATsc calls were ambiguous (results/2026-10-29_near_tie/CANDIDATE_RECORDS.md, PR #219). Curator decisions of 2026-10-30: draft from our own gene models (tier 3), scope-only family per genus or species.

  • MATss (genus Saccharomycopsis): 2 records of S. schoenii GDD12 chromosome IV (left alpha sub-cluster, right palindromic cassette), homothallic, genetic code table 12. Evidence: Kriti et al. G3 2026 (10.1093/g3journal/jkag067), Dost et al. 2024 (10.1016/j.micres.2024.127691). The authors' GTF is not public (GitHub and Zenodo hold scripts only), so models were rebuilt from the public RNA-seq (results/2026-10-29_ss_records).
  • MATpf (species Petasospora fabianii): MATa (JOY008) and MATalpha (TBRC 4498); AUGUSTUS + miniprot, no RNA-seq exists.
  • MATbz (genus Barnettozyma): one combined PB4207 record; MATalpha2 not modelled; no RNA-seq.

All five: curate-db propose and validate pass (Slurm 31446171), tier 3, needs_review, proposals only in db/candidates. Full suite 1600 passed. Open points are listed in results/2026-10-30_saccharomycopsis/README.md: homeodomain gene naming (MATa1 vs MATalpha2 cannot be told by domain search), partial SLA2 ORFs, label registry codes for the three new families (not added; frozen codes need approval), and the scope choices.

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hyphaltip and others added 5 commits October 30, 2026 06:08
…ne models, table 12); tests

Co-Authored-By: Claude Sonnet 5.5 <[email protected]>
…(P. fabianii MATa and MATalpha, B. californica PB4207); annotation work for both genera

Co-Authored-By: Claude Sonnet 5.5 <[email protected]>
…lic expectation for other species documented

Co-Authored-By: Claude Sonnet 5.5 <[email protected]>
…schoenii records rebuilt with corrected gene names (HMG-like ORF is MATalpha2, left homeodomain MATa1, MATa2 added in the right cassette); B. californica gets a partial MATalpha2

Co-Authored-By: Claude Sonnet 5.5 <[email protected]>
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